"I know we all agree we do not condone the use of illegal drugs," he said. PROMETHAZINE WITH CODEINE COUGH SYRUP (Promethazine Hydrochloride 6.25 mg/5mL & Codeine Phosphate 10 mg/5 mL) CV (Contains alcohol 7.0% v/v) Morton Grove Pharmaceuticals, Inc.: Promethazine hydrochloride and codeine phosphate syrup is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. That's the same place that people who use heroin speak of coming from." This is where policing the drug's online footprint gets murky. Inactive Ingredients: Artificial raspberry flavor, ascorbic acid, citric acid anhydrous, D&C Red #33, dehydrated alcohol, edetate disodium, FD&C Blue #1, glycerin, liquid sugar, methylparaben, purified water, saccharin sodium, sodium benzoate, sodium citrate dihydrate and sodium propionate.Codeine is one of the naturally occurring phenanthrene alkaloids of opium derived from the opium poppy; it is classified pharmacologically as a narcotic analgesic. The Cook County medical examiner's office, meanwhile, recorded only one death over the last three years that involved an ingredient used in the syrup (promethazine). Ostensibly a treatment for upper respiratory problems, promethazine is an antihistamine with allergy-fighting and sedative properties, while codeine is a painkiller. It has a molecular weight of 320.88, a molecular formula of CCodeine has good antitussive activity, although less than that of morphine at equal doses. But the presence of thousands of sizzurp images on Instagram — many hashtagged with the words "Morton Grove" — suggest such policies are difficult to enforce. Neither Morton Grove Pharmaceuticals, nor its parent company Wockhardt USA, responded to multiple requests for comment. And since another drug maker announced last year it was pulling its codeine cough syrup from the market — reportedly because of the way its recreational use had been glamorized — Morton Grove Pharmaceuticals has become arguably the best-known supplier of sizzurp's active ingredients. It has a molecular weight of 406.37, a molecular formula of CPromethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. Compared to other opiates like heroin, morphine and hydrocodone, sizzurp is a relatively minor threat. The middle class, predominantly white suburb north of Chicago would seem to have little to do with the phenomenon whose origins are generally credited to the Southern rap scene but whose cultural impact has spread far beyond. On Instagram and other platforms, many people simply share photos of their purple cocktails, but some openly inquire about how to get promethazine-codeine cough syrup while others tout their ability to procure the drug. Morton Grove Pharmaceuticals is touted on its website as a "leading manufacturer and marketer of oral liquid and topical pharmaceuticals." Though some of the online images show syrup bottles with labels from a Walgreens or other pharmacies, the company said the "biggest risk" is from people who obtain unused cough syrup from a friend or relative who obtained it through legal means. But sizzurp also has been suspected or a known contributor to several rappers' health crises or deaths: DJ Screw died in 2000 of an overdose ascribed to cough syrup and other substances. Codeine is metabolized primarily in the liver by enzymes of the endoplasmic reticulum, where it undergoes O-demethylation, N-demethylation, and partial conjugation with glucuronic acid. Learn what other patients are saying about Codeine and Morton Grove Pharmaceuticals.
Nausea is minimal after usual oral doses of codeine.Narcotic analgesics cause histamine release, which appears to be responsible for wheals or urticaria sometimes seen at the site of injection on parenteral administration. Morton Grove Pharmaceuticals, Inc.: Promethazine hydrochloride and codeine phosphate syrup is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. The brew inspired a slowed-down style of music known as "chopped and screwed" that has been employed by many Top 40 hit makers. Whatever the difficulties of policing the use of sizzurp, both on the streets and online, Friel, the Morton Grove village administrator, said the community will continue to put forth a positive image. Manufactured By: Morton Grove Pharmaceuticals, Inc. Morton Grove, IL 60053. Codeine is about 2/3 as effective orally as parenterally. A parade of rappers have spotlighted sizzurp. An Instagram spokesman said the social media company prohibits the use of its website to buy or sell prescription or illegal drugs or to promote recreational drug use. Yet sizzurp is technically legal as long as the cough syrup was obtained through a legitimate prescription. But Sally Thoren of Gateway Services in Chicago, which runs a residential treatment center for teen boys, said the drug has grown popular among her clientele over the last two years. The U.S. Substance Abuse and Mental Health Services Administration found that codeine was the cause for about 11,000 emergency room visits in 2011, the most recent year available, while hydrocodone and oxycodone were responsible for 97,000 and 175,000 visits, respectively. It is used in preference to morphine, because side effects are infrequent at the usual antitussive dose of codeine.Codeine in oral therapeutic dosage does not usually exert major effects on the cardiovascular system.Narcotic analgesics may cause nausea and vomiting by stimulating the chemoreceptor trigger zone (CTZ); however, they also depress the vomiting center, so that subsequent doses are unlikely to produce vomiting. It is soluble in water and freely soluble in alcohol. Variations on the theme include "mortongrovepharma," "mortongrovepurple" and "mortongrovepharmaceuticals" hashtags. This site is provided for educational and informational purposes only, in accordance with our Death Related to Ultra-Rapid Metabolism of Codeine to MorphineRisks from Concomitant Use with Benzodiazepines or Other CNS DepressantsConcomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death (see WARNINGS — Death Related to Ultra Rapid Metabolism of Codeine to Morphine Yet Morton Grove is home to a pharmaceutical company of the same name.